Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0L6HY
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| Former ID |
DNC008634
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| Drug Name |
1-(Bis-biphenyl-4-yl-methyl)-1H-imidazole
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [529625] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C28H22N2
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| Canonical SMILES |
C1=CC=C(C=C1)C2=CC=C(C=C2)C(C3=CC=C(C=C3)C4=CC=CC=C4)N5<br />C=CN=C5
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| InChI |
1S/C28H22N2/c1-3-7-22(8-4-1)24-11-15-26(16-12-24)28(30-20-19-29-21-30)27-17-13-25(14-18-27)23-9-5-2-6-10-23/h1-21,28H
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| InChIKey |
CKRNCVRILASGRW-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | 17 alpha-hydroxylase-C17, 20-lyase | Target Info | Inhibitor | [529625] | |
| PathWhiz Pathway | Androgen and Estrogen Metabolism | ||||
| Steroidogenesis | |||||
| References | |||||
| Ref 529625 | Bioorg Med Chem. 2008 Aug 15;16(16):7715-27. Epub 2008 Jul 9.Synthesis, biological evaluation, and molecular modeling studies of methylene imidazole substituted biaryls as inhibitors of human 17alpha-hydroxylase-17,20-lyase (CYP17)--part II: Core rigidification and influence of substituents at the methylene bridge. | ||||
| Ref 529625 | Bioorg Med Chem. 2008 Aug 15;16(16):7715-27. Epub 2008 Jul 9.Synthesis, biological evaluation, and molecular modeling studies of methylene imidazole substituted biaryls as inhibitors of human 17alpha-hydroxylase-17,20-lyase (CYP17)--part II: Core rigidification and influence of substituents at the methylene bridge. | ||||
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