Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0L3TR
|
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| Former ID |
DIB005743
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| Drug Name |
Estetrol
|
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| Synonyms |
Estetrol (oral, contraception/hormone deficiency/osteoporosis/cardiovascular disease/autoimmune disease/breast cancer/prostate cancer); Estetrol (oral, contraception/hormone deficiency/osteoporosis/cardiovascular disease/autoimmune disease/breast cancer/prostate cancer), Pantarhei; Estrogen receptor modulator (oral, contraception/hormone deficiency/autoimmune disease/breast cancer/prostate cancer/osteoporosis/cardiovascular disease), Pantarhei
|
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| Drug Type |
Small molecular drug
|
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| Indication | Autoimmune diabetes [ICD10:E08-E13] | Phase 2 | [522168] | ||
| Company |
Pantarhei Bioscience BV
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| Structure |
|
Download2D MOL |
|||
| Formula |
C18H24O4
|
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| Canonical SMILES |
c1c(cc2c(c1)[C@@H]1[C@@H](CC2)[C@H]2[C@](CC1)([C@H]([C@<br />@H]([C@@H]2O)O)O)C)O
|
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| CAS Number |
CAS 15183-37-6
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Estrogen receptor | Target Info | Modulator | [550049] | |
| Pathway Interaction Database | Regulation of nuclear SMAD2/3 signaling | ||||
| Signaling events mediated by HDAC Class II | |||||
| Plasma membrane estrogen receptor signaling | |||||
| LKB1 signaling events | |||||
| Regulation of Telomerase | |||||
| ATF-2 transcription factor network | |||||
| AP-1 transcription factor network | |||||
| FOXM1 transcription factor network | |||||
| Validated nuclear estrogen receptor alpha network | |||||
| Signaling mediated by p38-alpha and p38-beta | |||||
| FOXA1 transcription factor network | |||||
| References | |||||
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