Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0L3KR
|
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| Former ID |
DNC013339
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| Drug Name |
2,2',4,4'-tetrahydroxy-6'-methoxychalcone
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C16H14O6
|
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| Canonical SMILES |
COC1=CC(=CC(=C1C(=O)C=CC2=C(C=C(C=C2)O)O)O)O
|
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| InChI |
1S/C16H14O6/c1-22-15-8-11(18)7-14(21)16(15)12(19)5-3-9-2-4-10(17)6-13(9)20/h2-8,17-18,20-21H,1H3/b5-3+
|
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| InChIKey |
NNOIQNQJIKZQCN-HWKANZROSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Tyrosine oxidase | Target Info | Inhibitor | [1] | |
| BioCyc Pathway | (S)-reticuline biosynthesis | ||||
| Eumelanin biosynthesis | |||||
| L-dopachrome biosynthesis | |||||
| KEGG Pathway | Tyrosine metabolism | ||||
| Riboflavin metabolism | |||||
| Metabolic pathways | |||||
| Melanogenesis | |||||
| PathWhiz Pathway | Riboflavin Metabolism | ||||
| Tyrosine Metabolism | |||||
| WikiPathways | Dopamine metabolism | ||||
| References | |||||
| REF 1 | Bioorg Med Chem. 2007 Mar 15;15(6):2396-402. Epub 2007 Jan 17.Synthesis and evaluation of 2',4',6'-trihydroxychalcones as a new class of tyrosinase inhibitors. | ||||
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