TTD | Drug: D0K9XV

Drug General Information
Drug ID	D0K9XV
Former ID	DNC013208
Drug Name	N1-(4-fluorobenzyl)-2-benzyl-N3-hydroxymalonamide
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528703]
Structure		Download 2D MOL 3D MOL
Formula	C17H17FN2O3
Canonical SMILES	C1=CC=C(C=C1)CC(C(=O)NCC2=CC=C(C=C2)F)C(=O)NO
InChI	1S/C17H17FN2O3/c18-14-8-6-13(7-9-14)11-19-16(21)15(17(22)20-23)10-12-4-2-1-3-5-12/h1-9,15,23H,10-11H2,(H,19,21)(H,20,22)
InChIKey	HPODXRZHNDBMJC-UHFFFAOYSA-N
PubChem Compound ID	16114884
Target and Pathway
Target(s)	Aminopeptidase N	Target Info	Inhibitor	[528703]
BioCyc Pathway	Glutathione-mediated detoxification
KEGG Pathway	Glutathione metabolism
	Metabolic pathways
	Renin-angiotensin system
	Hematopoietic cell lineage
Pathway Interaction Database	C-MYB transcription factor network
PathWhiz Pathway	Glutathione Metabolism
Reactome	Metabolism of Angiotensinogen to Angiotensins
WikiPathways	Metabolism of Angiotensinogen to Angiotensins
	Cardiac Progenitor Differentiation
	miR-targeted genes in squamous cell - TarBase
	miR-targeted genes in muscle cell - TarBase
	miR-targeted genes in lymphocytes - TarBase
	miR-targeted genes in leukocytes - TarBase
	Glutathione metabolism
References
Ref 528703	J Med Chem. 2007 Mar 22;50(6):1322-34. Epub 2007 Feb 28.Novel selective inhibitors of the zinc plasmodial aminopeptidase PfA-M1 as potential antimalarial agents.
Ref 528703	J Med Chem. 2007 Mar 22;50(6):1322-34. Epub 2007 Feb 28.Novel selective inhibitors of the zinc plasmodial aminopeptidase PfA-M1 as potential antimalarial agents.

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Drug Information