Drug Information
Drug General Information | |||||
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Drug ID |
D0K0IS
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Former ID |
DIB007295
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Drug Name |
Polyglutamate camptothecin
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Synonyms |
CT-2106; PG-interferon; Polyglutamate camptothecin, Cell Therapeutics; Polyglutamate-camptothecin; CPT-Gly-PG; Camptothecin-glycine-polyglutamate; PG-CPT, Cell Therapeutics; PG-camptothecin, CT; Polyglutamate-linked anticancer agents, Cell Therapeutics; PG-G-CSF, Cell Therapeutics
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Indication | Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] | Phase 2 | [521802] | ||
Company |
Cell Therapeutics Inc
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Structure |
Download2D MOL |
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Canonical SMILES |
*C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](N*)CCC(=O)O)CCC(<br />=O)NCC(=O)O[C@@]1(CC)c2c(c(=O)n3c(c4c(C3)cc3c(n4)cccc3)<br />c2)COC1=O)CCC(=O)O
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Target and Pathway | |||||
Target(s) | Toposisomerase-1 | Target Info | Inhibitor | [528447] | |
NetPath Pathway | IL2 Signaling Pathway | ||||
PANTHER Pathway | DNA replication | ||||
Pathway Interaction Database | Caspase Cascade in Apoptosis | ||||
WikiPathways | Integrated Pancreatic Cancer Pathway | ||||
References |
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