Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0K0EK
|
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| Former ID |
DNC001146
|
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| Drug Name |
Prasterone
|
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| Drug Type |
Small molecular drug
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| Indication | Chronic obstructive pulmonary disease [ICD9: 490-492, 494-496; ICD10:J40-J44, J47] | Approved | [527619] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C19H28O2
|
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| Canonical SMILES |
CC12CCC3C(C1CCC2=O)CC=C4C3(CCC(C4)O)C
|
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| InChI |
1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h3,13-16,20H,4-11H2,1-2H3/t13-,14-,15-,16-,18-,19-/m0/s1
|
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| InChIKey |
FMGSKLZLMKYGDP-USOAJAOKSA-N
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| CAS Number |
CAS 53-43-0
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
1983, 4449, 75250, 596018, 837865, 841442, 3135651, 7885884, 8145544, 8153636, 11446567, 12014907, 12146065, 14751238, 14775640, 17404931, 24278369, 24702275, 26703947, 29224908, 46387028, 46508824, 47193749, 47959958, 48413520, 48415849, 49681751, 49747225, 49857278, 50172721, 53777474, 53788218, 56312069, 56312916, 56313484, 56313819, 56320669, 56320670, 57323014, 87566797, 91692812, 92297484, 92303742, 92308678, 92309040, 92709895, 93167098, 96025095, 103302695, 104095449
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| ChEBI ID |
ChEBI:28689
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| SuperDrug ATC ID |
A14AA07
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| SuperDrug CAS ID |
cas=000053430
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| Target and Pathway | |||||
| Target(s) | Glucose-6-phosphate dehydrogenase | Target Info | Inhibitor | [537753] | |
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| PathWhiz Pathway | Pentose Phosphate Pathway | ||||
| Warburg Effect | |||||
| Reactome | TP53 Regulates Metabolic Genes | ||||
| WikiPathways | Sulfation Biotransformation Reaction | ||||
| NRF2 pathway | |||||
| Nuclear Receptors Meta-Pathway | |||||
| Vitamin D Receptor Pathway | |||||
| miR-targeted genes in muscle cell - TarBase | |||||
| miR-targeted genes in lymphocytes - TarBase | |||||
| miR-targeted genes in leukocytes - TarBase | |||||
| miR-targeted genes in epithelium - TarBase | |||||
| Cori Cycle | |||||
| Metabolism of carbohydrates | |||||
| Pentose Phosphate Pathway | |||||
| Glutathione metabolism | |||||
| References | |||||
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