Drug Information

Drug General Information
Drug ID
D0J8ZH
Former ID
DNC009180
Drug Name
4'-Demethyl-4beta-amino-4-desoxypodophyllotoxin
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551351]
Structure
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2D MOL

3D MOL
Formula
C21H21NO7
Canonical SMILES
COC1=CC(=CC(=C1O)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)<br />N
InChI
1S/C21H21NO7/c1-25-15-3-9(4-16(26-2)20(15)23)17-10-5-13-14(29-8-28-13)6-11(10)19(22)12-7-27-21(24)18(12)17/h3-6,12,17-19,23H,7-8,22H2,1-2H3/t12-,17+,18-,19+/m0/s1
InChIKey
WZTRSUUEQXXWCN-JHQYFNNDSA-N
PubChem Compound ID
10927468
Target and Pathway
Target(s) DNA topoisomerase II Target Info Inhibitor [551351]
References
Ref 551351Antitumor agents, 107. New cytotoxic 4-alkylamino analogues of 4'-demethyl-epipodophyllotoxin as inhibitors of human DNA topoisomerase II. J Nat Prod. 1989 May-Jun;52(3):606-13.
Ref 551351Antitumor agents, 107. New cytotoxic 4-alkylamino analogues of 4'-demethyl-epipodophyllotoxin as inhibitors of human DNA topoisomerase II. J Nat Prod. 1989 May-Jun;52(3):606-13.

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