Drug Information
Drug General Information | |||||
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Drug ID |
D0J6XC
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Former ID |
DIB018046
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Drug Name |
tiratricol
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Synonyms |
TRIAC; 3,3',5-triiodothyroacetic acid
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Drug Type |
Small molecular drug
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Indication | Wound healing [ICD10:T14.0-T14.1] | Clinical trial | [539702] | ||
Structure |
Download2D MOL |
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Formula |
C14H9I3O4
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InChI |
InChI=1S/C14H9I3O4/c15-9-6-8(1-2-12(9)18)21-14-10(16)3-7(4-11(14)17)5-13(19)20/h1-4,6,18H,5H2,(H,19,20)
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InChIKey |
UOWZUVNAGUAEQC-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
827844, 827845, 827846, 827962, 855525, 4401016, 7885356, 8153574, 10321449, 11112109, 11466230, 11467350, 11485840, 14912191, 24900466, 26737090, 26737092, 26737109, 26737501, 29224836, 46504696, 46518914, 47349482, 47943909, 48019053, 48094654, 48426110, 49698385, 50100372, 50610406, 51091552, 53788806, 56261036, 57322967, 57654700, 85756745, 85788050, 91722578, 92125149, 103219116, 103913943, 104310301, 119526441, 121362089, 121362820, 124772192, 124881906, 124881907, 124881908, 126408229
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Target and Pathway | |||||
Target(s) | Thyroid hormone receptor alpha | Target Info | Agonist | [531482] | |
Thyroid hormone receptor beta-1 | Target Info | Agonist | [531482] | ||
References | |||||
Ref 531482 | Binding of 3,5,3'-triiodothyronine (T3) and its analogs to the in vitro translational products of c-erbA protooncogenes: differences in the affinity of the alpha- and beta-forms for the acetic acid analog and failure of the human testis and kidney alpha-2 products to bind T3. Mol Endocrinol. 1990 Feb;4(2):227-34. |
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