Drug General Information
Drug ID	D0J6TU
Former ID	DNC013858
Drug Name	5-(4-Chlorophenyl)-4-(4-methoxyphenyl)isothiazole
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529881]
Structure		Download 2D MOL 3D MOL
Formula	C16H12ClNOS
Canonical SMILES	COC1=CC=C(C=C1)C2=C(SN=C2)C3=CC=C(C=C3)Cl
InChI	1S/C16H12ClNOS/c1-19-14-8-4-11(5-9-14)15-10-18-20-16(15)12-2-6-13(17)7-3-12/h2-10H,1H3
InChIKey	XGOLGQNTCHMSDA-UHFFFAOYSA-N
PubChem Compound ID	44564457
Target and Pathway
Target(s)	Prostaglandin G/H synthase 1	Target Info	Inhibitor	[529881]
BioCyc Pathway	C20 prostanoid biosynthesis
KEGG Pathway	Arachidonic acid metabolism
	Metabolic pathways
	Platelet activation
	Serotonergic synapse
NetPath Pathway	TGF_beta_Receptor Signaling Pathway
PANTHER Pathway	Inflammation mediated by chemokine and cytokine signaling pathway
PathWhiz Pathway	Arachidonic Acid Metabolism
WikiPathways	Prostaglandin Synthesis and Regulation
	Arachidonic acid metabolism
	Phase 1 - Functionalization of compounds
	Eicosanoid Synthesis
	Selenium Micronutrient Network
References
Ref 529881	Bioorg Med Chem. 2009 Jan 15;17(2):558-68. Epub 2008 Dec 6.Diaryl-dithiolanes and -isothiazoles: COX-1/COX-2 and 5-LOX-inhibitory, *OH scavenging and anti-adhesive activities.
Ref 529881	Bioorg Med Chem. 2009 Jan 15;17(2):558-68. Epub 2008 Dec 6.Diaryl-dithiolanes and -isothiazoles: COX-1/COX-2 and 5-LOX-inhibitory, *OH scavenging and anti-adhesive activities.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.