Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0J4PB
|
||||
| Former ID |
DIB010834
|
||||
| Drug Name |
GW 597599
|
||||
| Indication | Mood disorder [ICD10:F30-F39] | Phase 2 | [1] | ||
| Company |
GlaxoSmithKline
|
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| Structure |
|
Download2D MOL |
|||
| Target and Pathway | |||||
| Target(s) | Substance-P receptor | Target Info | Antagonist | [2] | |
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Measles | |||||
| PANTHER Pathway | CCKR signaling map ST | ||||
| Reactome | G alpha (q) signalling events | ||||
| WikiPathways | SIDS Susceptibility Pathways | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| Spinal Cord Injury | |||||
| Peptide GPCRs | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015473) | ||||
| REF 2 | Application of LC-NMR to the identification of bulk drug impurities in NK1 antagonist GW597599 (vestipitant). Magn Reson Chem. 2010 Jul;48(7):523-30. | ||||
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