Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0J0TD
|
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| Former ID |
DIB016367
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| Drug Name |
CC-408
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| Drug Type |
Small molecular drug
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| Indication | Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] | Investigative | [1] | ||
| Company |
Samada Research
|
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| Structure |
|
Download2D MOL |
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| Formula |
C18H21NO4
|
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| Canonical SMILES |
CN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)OC)O4)O
|
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| InChI |
1S/C18H21NO4/c1-19-8-7-17-14-10-3-4-12(22-2)15(14)23-16(17)11(20)5-6-18(17,21)13(19)9-10/h3-4,13,16,21H,5-9H2,1-2H3/t13-,16+,17+,18-/m1/s1
|
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| InChIKey |
BRUQQQPBMZOVGD-XFKAJCMBSA-N
|
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| CAS Number |
CAS 76-42-6
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
10218, 81987, 7980232, 11039373, 14825887, 14923583, 16697449, 39317907, 46508908, 47207011, 48416366, 49993158, 50887162, 56464157, 85242752, 92714668, 103189261, 104133805, 117497014, 126629457, 127559039, 134222776, 134337597, 135269853, 137001259, 139157519, 152101652, 160849697, 160963843, 162224649, 175266292, 178103671, 179116835, 184548425, 223656812, 223800482, 226395100
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| Target and Pathway | |||||
| Target(s) | Mu-type opioid receptor | Target Info | Modulator | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Estrogen signaling pathway | |||||
| Morphine addiction | |||||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Enkephalin release | |||||
| Pathway Interaction Database | IL4-mediated signaling events | ||||
| Reactome | Peptide ligand-binding receptors | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | TCR Signaling Pathway | ||||
| GPCRs, Class A Rhodopsin-like | |||||
| Peptide GPCRs | |||||
| Opioid Signalling | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 319). | ||||
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