Drug General Information
Drug ID
D0I8FI
Former ID
DAP000080
Drug Name
Isoproterenol
Synonyms
Aerolone; Aleudrine; Aludrin; Aludrine; Asiprenol; Asmalar; Assiprenol; Bellasthman; Bronkephrine; Dihydroxyphenylethanolisopropylamine; Euspiran; ISOPROP; Isadrin; Isadrine; Isonorene; Isonorin; Isoprenalin; Isoprenaline; Isopropydrin; Isopropyladrenaline; Isopropylarterenol; Isopropylnoradrenaline; Isopropylnorepinephrine; Isoproterenolum; Isorenin; Isuprel; Isupren; Izadrin; Lomupren; Neodrenal; Norisodrine; Novodrin; Proternol; Respifral; Saventrine; Epinephrine isopropyl homolog; Isoprenaline hydrochloride; Isopropyl noradrenaline; Isoproterenol Chloride; Isoproterenol [JAN]; Isuprel Mistometer; Racemic isoprenaline; Racemic isoproterenol; WIN 5162; D-Isoprenaline; D-Isopropylarterenol; D-Isoproterenol; DL-Isopropylnorepinephrine; Dl-Ipr; Dl-Isadrine; Dl-Isopropylnoradrenaline; Isoprenalina [INN-Spanish]; Isoprenaline (INN); Isoprenalinum [INN-Latin]; Isuprel (TN); L-Isopropylnoradrenaline; L-Isoproterenol; Medihaler-ISO; N-Isopropylnoradrenaline; N-Isopropylnorepinephrine; Neo-Epinine; Vapo-Iso; Alpha-(Isopropylaminomethyl)protocatechuyl alcohol; Alpha-(Isopropylaminomoethyl)protocatechuyl alcohol; D-N-Isopropylnorepinephrine; Dl-N-Isopropylnoradrenaline; Vapo-N-iso; Isopropylaminomethyl(3,4-dihydroxyphenyl)carbinol; Isopropylaminomethyl-3,4-dihydroxyphenyl carbinol; DL(+-)-Isoproterenol; N-Isopropyl-beta-dihydroxyphenyl-beta-hydroxyethylamine; (+)-Isoprenaline; (+)-Isoproterenol; (+-)-Isoprenaline; (+-)-Isoproterenol; (-)-Isoproterenol hydrochloride; (S)-(+)-Isoproterenol; (S)-Isoprenaline; (S)-Isoproterenol; 1,2-Benzenediol, 4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-(9CI); 1,2-Benzenediol, 4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-, (S)-(9CI); 1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanol; 1-(3,4-Dihydroxyphenyl)-2-isopropylaminoethanol; 3,4-Dihydroxy-.alpha.-(isopropylaminomethyl)-benzyl alcohol; 3,4-Dihydroxy-.alpha.-[(isopropylamino)methyl]benzyl alcohol; 3,4-Dihydroxy-alpha-((isopropylamino)methyl)benzyl alcohol; 4-(1-Hydroxy-2(isopropylamino)ethyl)-benzene 1,2-diol; 4-(1-Hydroxy-2-((1-methylethyl)amino)ethyl)-1,2-benzenediol; 4-{1-hydroxy-2-[(1-methylethyl)amino]ethyl}benzene-1,2-diol
Drug Type
Small molecular drug
Indication Bradycardia; Heart block [ICD9: 116.0, 426.9; ICD10:B40, I44-I45] Approved [538350]
Therapeutic Class
Cardiotonic Agents
Company
Abbott Laboratories
Structure
Download
2D MOL

3D MOL

Formula
C11H17NO3
Canonical SMILES
CC(C)NCC(C1=CC(=C(C=C1)O)O)O
InChI
1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3
InChIKey
JWZZKOKVBUJMES-UHFFFAOYSA-N
CAS Number
CAS 7683-59-2
PubChem Compound ID
PubChem Substance ID
ChEBI ID
ChEBI:6046
SuperDrug ATC ID
C01CA02; R03AB02; R03CB01
SuperDrug CAS ID
cas=007683592
Target and Pathway
Target(s) Beta-2 adrenergic receptor Target Info Modulator [556264]
KEGG Pathway Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Endocytosis
Adrenergic signaling in cardiomyocytes
Salivary secretion
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Beta2 adrenergic receptor signaling pathway
Pathway Interaction Database Arf6 trafficking events
Arf6 signaling events
Reactome Adrenoceptors
G alpha (s) signalling events
WikiPathways Monoamine GPCRs
Calcium Regulation in the Cardiac Cell
GPCRs, Class A Rhodopsin-like
Vitamin D Receptor Pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 538350FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 083346.
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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