Drug Information

Drug General Information
Drug ID
D0I5HE
Former ID
DPR000082
Drug Name
NPY5RA-972
Drug Type
Small molecular drug
Indication Obesity [ICD9: 278; ICD10:E66] Preclinical [536122]
Company
AstraZeneca
Structure
Download
2D MOL

3D MOL
Formula
C21H25N3O2
Canonical SMILES
CC1=C(C=CC2=C1C3=CC=CC=C3N2C(C)C)NC(=O)N4CCOCC4
InChI
1S/C21H25N3O2/c1-14(2)24-18-7-5-4-6-16(18)20-15(3)17(8-9-19(20)24)22-21(25)23-10-12-26-13-11-23/h4-9,14H,10-13H2,1-3H3,(H,22,25)
InChIKey
ZNFMHLDBJPAFEQ-UHFFFAOYSA-N
PubChem Compound ID
9884833
PubChem Substance ID
14852017, 24171683, 45631774, 78861346, 103344618, 104010267, 135698912, 143102940, 163124928, 204362841, 232511789, 241376577, 249241502, 249617949, 252157446
Target and Pathway
Target(s) Neuropeptide Y receptor 5 Target Info Antagonist [536122]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 536122Emerging drugs for obesity: linking novel biological mechanisms to pharmaceutical pipelines. Expert Opin Emerg Drugs. 2005 Aug;10(3):643-60.
Ref 536122Emerging drugs for obesity: linking novel biological mechanisms to pharmaceutical pipelines. Expert Opin Emerg Drugs. 2005 Aug;10(3):643-60.

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