Drug General Information
Drug ID
D0I0WP
Former ID
DNC009407
Drug Name
4-(methyl(4-phenylthiazol-2-yl)amino)phenol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529388]
Structure
Download
2D MOL

3D MOL

Formula
C16H14N2OS
Canonical SMILES
CN(C1=CC=C(C=C1)O)C2=NC(=CS2)C3=CC=CC=C3
InChI
1S/C16H14N2OS/c1-18(13-7-9-14(19)10-8-13)16-17-15(11-20-16)12-5-3-2-4-6-12/h2-11,19H,1H3
InChIKey
XDKOSPFALAXPJO-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Collagenase 3 Target Info Inhibitor [529388]
NetPath Pathway IL1 Signaling Pathway
PANTHER Pathway Alzheimer disease-presenilin pathway
Plasminogen activating cascade
Pathway Interaction Database Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Reactome Collagen degradation
Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
Assembly of collagen fibrils and other multimeric structures
WikiPathways Endochondral Ossification
Activation of Matrix Metalloproteinases
Oncostatin M Signaling Pathway
AGE/RAGE pathway
Matrix Metalloproteinases
References
Ref 529388Bioorg Med Chem. 2009 Feb 1;17(3):990-1005. Epub 2008 Mar 6.High throughput screening of potentially selective MMP-13 exosite inhibitors utilizing a triple-helical FRET substrate.
Ref 529388Bioorg Med Chem. 2009 Feb 1;17(3):990-1005. Epub 2008 Mar 6.High throughput screening of potentially selective MMP-13 exosite inhibitors utilizing a triple-helical FRET substrate.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.