Drug Information

Drug General Information
Drug ID
D0HQ3A
Former ID
DIB015422
Drug Name
ELGODIPINE HYDROCHLORIDE
Synonyms
IQB-875; Elgodipine hydrochloride < Rec INNM >; Rac-2,6-Dimethyl-4-(2,3-methylenedioxyphenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-isopropyl 5-[2-[N-(4-fluorobenzyl)-N-methylamino]ethyl] diester monohydrochloride
Drug Type
Small molecular drug
Indication Angina pectoris [ICD9: 413; ICD10:I20] Discontinued in Phase 3 [544620]
Structure
Download
2D MOL

3D MOL
Formula
C29H33FN2O6
Canonical SMILES
CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=C3C(=CC=C2)OCO3)C(=O)O<br />CCN(C)CC4=CC=C(C=C4)F
InChI
1S/C29H33FN2O6/c1-17(2)38-29(34)25-19(4)31-18(3)24(26(25)22-7-6-8-23-27(22)37-16-36-23)28(33)35-14-13-32(5)15-20-9-11-21(30)12-10-20/h6-12,17,26,31H,13-16H2,1-5H3
InChIKey
ZGRIPYHIFXGCHR-UHFFFAOYSA-N
CAS Number
CAS 119413-55-7
PubChem Compound ID
60701
PubChem Substance ID
8187014, 14909773, 43118057, 57314071, 80652491, 104321419, 117509926, 126422365, 134224316, 135017835, 139740863, 163333073, 179149673, 184547474, 226433125
Target and Pathway
Target(s) Calcium channel Target Info Agonist [527236], [551871]
References
Ref 544620Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000324)
Ref 527236The calcium channel blocker amlodipine exerts its anti-proliferative action via p21(Waf1/Cip1) gene activation. FASEB J. 2004 Oct;18(13):1516-23.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.