Drug Information

Drug General Information
Drug ID
D0HO1O
Former ID
DIB018550
Drug Name
2ewy
Drug Type
Small molecular drug
Indication Discovery agent Investigative [543245]
Structure
Download
2D MOL
Formula
C33H32N2O3
InChI
InChI=1S/C33H32N2O3/c1-23-10-9-13-25(18-23)21-34-22-30(36)29(19-24-11-3-2-4-12-24)35-33(37)28-20-26-14-5-7-16-31(26)38-32-17-8-6-15-27(28)32/h2-18,20,29-30,34,36H,19,21-22H2,1H3,(H,35,37)/t29-,30+/m0/s1
InChIKey
BNWZCXDHHPBQOX-XZWHSSHBSA-N
PubChem Compound ID
11963503
PubChem Substance ID
17422360, 23920023, 36460674, 46394072, 50172180, 243575960, 252166888
Target and Pathway
Target(s) beta-site APP-cleaving enzyme 2 Target Info Inhibitor [527894]
References
Ref 543245(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8688).
Ref 527894Crystal structure of human BACE2 in complex with a hydroxyethylamine transition-state inhibitor. J Mol Biol. 2006 Jan 13;355(2):249-61. Epub 2005 Nov 8.

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