Drug General Information
Drug ID	D0H7JJ
Former ID	DNC009666
Drug Name	Sodium sulfamate
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529905]
Structure		Download 2D MOL 3D MOL
Formula	H2NNaO3S
Canonical SMILES	NS(=O)(=O)[O-].[Na+]
InChI	1S/H3NO3S.Na/c1-5(2,3)4;/h(H3,1,2,3,4);/q;+1/p-1
InChIKey	QDWYPRSFEZRKDK-UHFFFAOYSA-M
PubChem Compound ID	23700090
Target and Pathway
Target(s)	Carbonic anhydrase IV	Target Info	Inhibitor	[529905]
KEGG Pathway	Nitrogen metabolism
	Proximal tubule bicarbonate reclamation
Reactome	Erythrocytes take up carbon dioxide and release oxygen
	Erythrocytes take up oxygen and release carbon dioxide
	Reversible hydration of carbon dioxide
WikiPathways	Reversible Hydration of Carbon Dioxide
	Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
	Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
References
Ref 529905	Bioorg Med Chem Lett. 2009 Feb 15;19(4):1155-8. Epub 2008 Dec 25.Carbonic anhydrase inhibitors: the membrane-associated isoform XV is highly inhibited by inorganic anions.
Ref 529905	Bioorg Med Chem Lett. 2009 Feb 15;19(4):1155-8. Epub 2008 Dec 25.Carbonic anhydrase inhibitors: the membrane-associated isoform XV is highly inhibited by inorganic anions.

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