Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0H3CV
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| Former ID |
DIB014976
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| Drug Name |
Ro-48-8724
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| Indication | Multidrug resistant infection [ICD10:A00-B99] | Terminated | [1] | ||
| Company |
F Hoffmann-La Roche Ltd
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
N12C(=O)[C@H]3N(C(=O)C(F)(F)F)C[C@H]([C@@H]13)CC(=C2C(=<br />O)[O-])COC(=O)N.[Na+]
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| CAS Number |
CAS 170581-96-1
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| Target and Pathway | |||||
| Target(s) | Beta-lactamase | Target Info | Modulator | [2] | |
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008187) | ||||
| REF 2 | Activity of a broad-spectrum cephalosporin (Ro 48-8391) alone and in combination with two novel beta-lactamase inhibitors (Ro 48-5545 and Ro 48-8724). Diagn Microbiol Infect Dis. 1998 Oct;32(2):85-94. | ||||
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