Drug General Information
Drug ID
D0H2NH
Former ID
DIB000425
Drug Name
BRIFENTANIL
Synonyms
Brifentanil < Rec INN; A-3331 (monohydrochloride); Rac-cis-1-[2-(4-Ethyl-4,5-dihydro-5-oxo-1H-tetrazol-1-yl)ethyl]-3-methyl-4-[N-(2-fluorophenyl)methoxyacetamido]piperidine; Rac-cis-N-[1-[2-(4-Ethyl-5-oxo-2-tetrazolin-1-yl)ethyl]-3-methyl-4-piperidyl]-2'-fluoro-2-methoxyacetanilide
Drug Type
Small molecular drug
Indication Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] Investigative [531532], [551871]
Structure
Download
2D MOL

3D MOL

Formula
C20H30ClFN6O3
Canonical SMILES
CCN1N=NN(CCN2CCC(C(C)C2)N(C(=O)COC)c3ccccc3F)C1=O
InChI
1S/C20H29FN6O3/c1-4-25-20(29)26(23-22-25)12-11-24-10-9-17(15(2)13-24)27(19(28)14-30-3)18-8-6-5-7-16(18)21/h5-8,15,17H,4,9-14H2,1-3H3
InChIKey
KKMGCTVJCQYQPV-UHFFFAOYSA-N
CAS Number
CAS 101345-71-5
PubChem Compound ID
Target and Pathway
Target(s) Opioid receptor Target Info Modulator [531532], [551871]
References
Ref 531532Synthesis and pharmacological evaluation of a series of new 3-methyl-1,4-disubstituted-piperidine analgesics. J Med Chem. 1990 Oct;33(10):2876-82.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 531532Synthesis and pharmacological evaluation of a series of new 3-methyl-1,4-disubstituted-piperidine analgesics. J Med Chem. 1990 Oct;33(10):2876-82.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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