| Drug General Information |
| Drug ID |
D0GY2T
|
| Former ID |
DNC002538
|
| Drug Name |
3-ISOBUTYL-1-METHYLXANTHINE
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C10H14N4O2
|
| Canonical SMILES |
CC(C)CN1C2=C(C(=O)N(C1=O)C)NC=N2
|
| InChI |
1S/C10H14N4O2/c1-6(2)4-14-8-7(11-5-12-8)9(15)13(3)10(14)16/h5-6H,4H2,1-3H3,(H,11,12)
|
| InChIKey |
APIXJSLKIYYUKG-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| PubChem Substance ID |
440021, 586297, 603446, 831838, 3139713, 4667750, 4667751, 6436339, 7888298, 7980296, 8150163, 8152377, 10517163, 11111325, 11120336, 11120824, 11121312, 11121752, 11122232, 11336097, 11361336, 11362907, 11364974, 11365469, 11367536, 11368031, 11370098, 11371005, 11371006, 11372975, 11373137, 11373632, 11374483, 11375698, 11376193, 11378269, 11404372, 11462308, 11485426, 11485546, 11489521, 11489551, 11491773, 11492866, 12157646, 14822728, 15195998, 17405203, 24277680, 24896107
|
| Target and Pathway |
| Target(s) |
Type IV phosphodiesterase |
Target Info |
Inhibitor |
[1]
|
|---|
| CGMP-specific 3',5'-cyclic phosphodiesterase |
Target Info |
Inhibitor |
[1]
|
| CGMP-dependent3',5'-cyclic phosphodiesterase |
Target Info |
Inhibitor |
[1]
|
|
KEGG Pathway
|
Purine metabolism
|
|
cAMP signaling pathway
|
|
Morphine addictionhsa00230:Purine metabolism
|
|
cGMP-PKG signaling pathwayhsa00230:Purine metabolism
|
|
cGMP-PKG signaling pathway
|
|
Morphine addiction
|
|
NetPath Pathway
|
TGF_beta_Receptor Signaling PathwayNetPath_23:TSH Signaling Pathway
|
|
PathWhiz Pathway
|
Purine Metabolism
|
|
Reactome
|
DARPP-32 events
|
|
G alpha (s) signalling eventsR-HSA-418457:cGMP effectsR-HSA-418457:cGMP effects
|
|
G alpha (s) signalling events
|
|
WikiPathways
|
G Protein Signaling Pathways
|
|
Myometrial Relaxation and Contraction Pathways
|
|
TSH signaling pathway
|
| References |
| REF 1 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
|---|
