Drug Information

Drug General Information
Drug ID
D0GV0Q
Former ID
DIB007164
Drug Name
BMY-43748
Synonyms
7-[3(S)-Aminopyrrolidin-1-yl]-1-(2,4-difluorophenyl)-6-fluoro-5-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylicacid
Drug Type
Small molecular drug
Indication Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] Phase 1 [531122]
Structure
Download
2D MOL

3D MOL
Formula
C22H20ClF3N4O3
Canonical SMILES
CC1=C2C(=O)C(=CN(C2=NC(=C1F)N3CC4CCC3CN4)C5=C(C=C(C=C5)<br />F)F)C(=O)O.Cl
InChI
1S/C22H19F3N4O3.ClH/c1-10-17-19(30)14(22(31)32)9-29(16-5-2-11(23)6-15(16)24)20(17)27-21(18(10)25)28-8-12-3-4-13(28)7-26-12;/h2,5-6,9,12-13,26H,3-4,7-8H2,1H3,(H,31,32);1H
InChIKey
WZPJEHNEEUMGGA-UHFFFAOYSA-N
CAS Number
CAS 132195-65-4
PubChem Compound ID
3071731
PubChem Substance ID
36404424, 49996943, 53629834, 111666466, 135218770
Target and Pathway
Target(s) DNA topoisomerase II Target Info Modulator [531122], [551871]
References
Ref 531122Comparative metabolism of tosufloxacin and BMY 43748 in hepatocytes from rat, dog, monkey and man. Toxicol In Vitro. 1993 Jul;7(4):499-503.
Ref 531122Comparative metabolism of tosufloxacin and BMY 43748 in hepatocytes from rat, dog, monkey and man. Toxicol In Vitro. 1993 Jul;7(4):499-503.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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