Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0GQ9A
|
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| Former ID |
DNC009667
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| Drug Name |
Sodium phenylarsonate
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C6H5AsNa2O3
|
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| Canonical SMILES |
C1=CC=C(C=C1)[As](=O)([O-])[O-].[Na+].[Na+]
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| InChI |
1S/C6H7AsO3.2Na/c8-7(9,10)6-4-2-1-3-5-6;;/h1-5H,(H2,8,9,10);;/q;2*+1/p-2
|
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| InChIKey |
IDQWLYXYOJVSLB-UHFFFAOYSA-L
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Carbonic anhydrase IV | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Nitrogen metabolism | ||||
| Proximal tubule bicarbonate reclamation | |||||
| Reactome | Erythrocytes take up carbon dioxide and release oxygen | ||||
| Erythrocytes take up oxygen and release carbon dioxide | |||||
| Reversible hydration of carbon dioxide | |||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | ||||
| Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | |||||
| Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes | |||||
| References | |||||
| REF 1 | Bioorg Med Chem Lett. 2009 Feb 15;19(4):1155-8. Epub 2008 Dec 25.Carbonic anhydrase inhibitors: the membrane-associated isoform XV is highly inhibited by inorganic anions. | ||||
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