Drug General Information
Drug ID
D0G8QW
Former ID
DNAP001470
Drug Name
Delapril
Synonyms
Adecut (TN)
Drug Type
Small molecular drug
Indication Cardiovascular disorder [ICD10:I00-I99] Approved [536361]
Company
Takeda
Structure
Download
2D MOL

3D MOL

Formula
C26H32N2O5
Canonical SMILES
CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N(CC(=O)O)C2CC3=CC=CC<br />=C3C2
InChI
1S/C26H32N2O5/c1-3-33-26(32)23(14-13-19-9-5-4-6-10-19)27-18(2)25(31)28(17-24(29)30)22-15-20-11-7-8-12-21(20)16-22/h4-12,18,22-23,27H,3,13-17H2,1-2H3,(H,29,30)/t18-,23-/m0/s1
InChIKey
WOUOLAUOZXOLJQ-MBSDFSHPSA-N
CAS Number
CAS 83435-66-9
PubChem Compound ID
PubChem Substance ID
SuperDrug ATC ID
C09AA12
Target and Pathway
Target(s) Angiotensin-converting enzyme Target Info Modulator [525822], [528275], [534314], [536361]
KEGG Pathway Renin-angiotensin system
Chagas disease (American trypanosomiasis)
Hypertrophic cardiomyopathy (HCM)
PathWhiz Pathway Angiotensin Metabolism
Reactome Metabolism of Angiotensinogen to Angiotensins
WikiPathways ACE Inhibitor Pathway
Metabolism of Angiotensinogen to Angiotensins
References
Ref 536361Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.
Ref 525822The influence of natural products upon drug discovery. Nat Prod Rep. 2000 Jun;17(3):215-34.
Ref 528275Drug discovery from natural sources. AAPS J. 2006 Apr 14;8(2):E239-53.
Ref 534314Natural products in drug discovery and development. J Nat Prod. 1997 Jan;60(1):52-60.
Ref 536361Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.

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