Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0G8OD
|
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| Former ID |
DNC005906
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| Drug Name |
N-(benzyloxycarbonyl)-leucyl-glycine-nitrile
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [527885] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C16H21N3O3
|
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| Canonical SMILES |
CC(C)CC(C(=O)NCC#N)NC(=O)OCC1=CC=CC=C1
|
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| InChI |
1S/C16H21N3O3/c1-12(2)10-14(15(20)18-9-8-17)19-16(21)22-11-13-6-4-3-5-7-13/h3-7,12,14H,9-11H2,1-2H3,(H,18,20)(H,19,21)/t14-/m0/s1
|
||||
| InChIKey |
UFXQLUZNMRVTPU-AWEZNQCLSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | Inhibitor | [527885] | |
| Cathepsin S | Target Info | Inhibitor | [527885] | ||
| Cathepsin K | Target Info | Inhibitor | [527885] | ||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| Activation of Matrix Metalloproteinases | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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