Drug General Information
Drug ID	D0G7HN
Former ID	DNC011918
Drug Name	4-Iodyl-benzoic acid
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[525449]
Structure		Download 2D MOL 3D MOL
Formula	C7H5IO4
Canonical SMILES	C1=CC(=CC=C1C(=O)O)I(=O)=O
InChI	1S/C7H5IO4/c9-7(10)5-1-3-6(4-2-5)8(11)12/h1-4H,(H,9,10)
InChIKey	OCPGBAXIXDSOBI-UHFFFAOYSA-N
PubChem Compound ID	3718733
Target and Pathway
Target(s)	mRNA of Protein tyrosine phosphatase-1B	Target Info	Inhibitor	[525449]
KEGG Pathway	Adherens junction
	Insulin signaling pathway
NetPath Pathway	FSH Signaling Pathway
PANTHER Pathway	Cadherin signaling pathway
Pathway Interaction Database	Insulin Pathway
	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
	Signaling events mediated by PTP1B
	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
	Signaling events mediated by TCPTP
	IGF1 pathway
	EGF receptor (ErbB1) signaling pathway
	Posttranslational regulation of adherens junction stability and dissassembly
	PDGFR-beta signaling pathway
	N-cadherin signaling events
Reactome	Integrin alphaIIb beta3 signaling
	Regulation of IFNG signaling
	Regulation of IFNA signaling
	Growth hormone receptor signaling
WikiPathways	Insulin Signaling
	Growth hormone receptor signaling
	Leptin signaling pathway
	Interferon gamma signaling
	Interferon alpha/beta signaling
	Integrin alphaIIb beta3 signaling
References
Ref 525449	Bioorg Med Chem Lett. 1999 Feb 8;9(3):353-6.Periodinates: a new class of protein tyrosine phosphatase inhibitors.
Ref 525449	Bioorg Med Chem Lett. 1999 Feb 8;9(3):353-6.Periodinates: a new class of protein tyrosine phosphatase inhibitors.

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