Drug General Information
Drug ID
D0G3SZ
Former ID
DNC011369
Drug Name
ALTENUSIN
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531262]
Structure
Download
2D MOL

3D MOL

Formula
C15H14O6
Canonical SMILES
CC1=CC(=C(C=C1C2=CC(=CC(=C2C(=O)O)O)OC)O)O
InChI
1S/C15H14O6/c1-7-3-11(16)12(17)6-9(7)10-4-8(21-2)5-13(18)14(10)15(19)20/h3-6,16-18H,1-2H3,(H,19,20)
InChIKey
ADPBTBPPIIKLEH-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Induced myeloid leukemia cell differentiation protein Mcl-1 Target Info Inhibitor [531262]
KEGG Pathway PI3K-Akt signaling pathway
MicroRNAs in cancer
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Apoptosis signaling pathway
CCKR signaling map ST
Pathway Interaction Database E2F transcription factor network
Direct p53 effectors
IL6-mediated signaling events
HIF-1-alpha transcription factor network
WikiPathways Apoptosis
miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBase
miR-targeted genes in leukocytes - TarBase
Apoptosis Modulation and Signaling
References
Ref 531262Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2).
Ref 531262Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2).

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.