Drug Information

Drug General Information
Drug ID
D0G2RE
Former ID
DNC000335
Drug Name
BN 50730
Drug Type
Small molecular drug
Indication Asthma [ICD10:J45] Discontinued in Phase 3 [544860]
Structure
Download
2D MOL

3D MOL
Formula
C26H23ClN6OS2
Canonical SMILES
CC1=NN=C2N1C3=C(C4=C(S3)CN(CC4)C(=S)NC5=CC=C(C=C5)OC)C(<br />=NC2)C6=CC=CC=C6Cl
InChI
1S/C26H23ClN6OS2/c1-15-30-31-22-13-28-24(18-5-3-4-6-20(18)27)23-19-11-12-32(14-21(19)36-25(23)33(15)22)26(35)29-16-7-9-17(34-2)10-8-16/h3-10H,11-14H2,1-2H3,(H,29,35)
InChIKey
WBGAFGNZNGJVNW-UHFFFAOYSA-N
CAS Number
CAS 68-41-7
PubChem Compound ID
3033963
PubChem Substance ID
10047856, 14910135, 36077773, 50064347, 56459414, 57352822, 74844164, 111635451, 129556584, 134339783, 135026067, 135073071, 138982552, 140393067, 160703462, 179323541, 184547757, 198943319, 227313458
ChEBI ID
ChEBI:40009
Target and Pathway
Target(s) Platelet-activating factor receptor Target Info Modulator
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Staphylococcus aureus infection
NetPath Pathway IL5 Signaling Pathway
Leptin Signaling Pathway
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (q) signalling events
Interferon gamma signaling
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Small Ligand GPCRs
Interferon gamma signaling
GPCR ligand binding
GPCR downstream signaling
References
Ref 544860Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001346)

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