Drug General Information
Drug ID
D0FF3D
Former ID
DNC000929
Drug Name
Metazamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [537753]
Structure
Download
2D MOL

3D MOL

Formula
C11H12N2O2
Canonical SMILES
CC1=CNC(=O)N1C2=CC=C(C=C2)OC
InChI
1S/C11H12N2O2/c1-8-7-12-11(14)13(8)9-3-5-10(15-2)6-4-9/h3-7H,1-2H3,(H,12,14)
InChIKey
NHUPEUMBGMETKD-UHFFFAOYSA-N
CAS Number
CAS 347396-82-1
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Glucose-6-phosphate dehydrogenase Target Info Inhibitor [537753]
BioCyc Pathway Pentose phosphate pathway
Pentose phosphate pathway (oxidative branch)
KEGG Pathway Pentose phosphate pathway
Glutathione metabolism
Metabolic pathways
Biosynthesis of antibiotics
Carbon metabolism
Central carbon metabolism in cancer
NetPath Pathway TGF_beta_Receptor Signaling Pathway
PathWhiz Pathway Pentose Phosphate Pathway
Warburg Effect
Reactome TP53 Regulates Metabolic Genes
WikiPathways Sulfation Biotransformation Reaction
NRF2 pathway
Nuclear Receptors Meta-Pathway
Vitamin D Receptor Pathway
miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBase
miR-targeted genes in leukocytes - TarBase
miR-targeted genes in epithelium - TarBase
Cori Cycle
Metabolism of carbohydrates
Pentose Phosphate Pathway
Glutathione metabolism
References
Ref 537753Glucose utilization and activity of glucose-6-phosphate dehydrogenase, isocitrate dehydrogenase and malate dehydrogenase in rat erythrocytes after treatment with tuberculostatic agents. Vopr Med Khim. 1986 Sep-Oct;32(5):32-5.
Ref 537753Glucose utilization and activity of glucose-6-phosphate dehydrogenase, isocitrate dehydrogenase and malate dehydrogenase in rat erythrocytes after treatment with tuberculostatic agents. Vopr Med Khim. 1986 Sep-Oct;32(5):32-5.

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