Drug General Information
Drug ID
D0F8HN
Former ID
DIB001796
Drug Name
DA-8031
Synonyms
Serotonin transporter inhibitor (premature ejaculation), Dong A
Indication Premature ejaculation [ICD9: 302.75; ICD10:F52.4] Phase 2 [524220]
Company
Dong-A Pharmaceutical Co Ltd
Target and Pathway
Target(s) Sodium-dependent serotonin transporter Target Info Inhibitor [532463]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway 5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
WikiPathways Monoamine Transport
SIDS Susceptibility Pathways
NRF2 pathway
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 524220ClinicalTrials.gov (NCT01798667) Clinical Trial to Evaluate the Efficacy and Safety of DA-8031 in Male Patients With Premature Ejaculation. U.S. National Institutes of Health.
Ref 532463Effect of DA-8031, a novel oral compound for premature ejaculation, on male rat sexual behavior. Int J Urol. 2014 Mar;21(3):325-9.

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