Drug General Information
Drug ID
D0F7NT
Former ID
DIB008633
Drug Name
349U85.HCL
Synonyms
6-Piperidinoquinolin-2(1H)-one hydrochloride
Drug Type
Small molecular drug
Indication Cardiovascular disorder [ICD10:I00-I99] Phase 1 [526644], [533980]
Structure
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2D MOL

3D MOL

Formula
C14H17ClN2O
Canonical SMILES
C1CCN(CC1)C2=CC3=C(C=C2)NC(=O)C=C3.Cl
InChI
1S/C14H16N2O.ClH/c17-14-7-4-11-10-12(5-6-13(11)15-14)16-8-2-1-3-9-16;/h4-7,10H,1-3,8-9H2,(H,15,17);1H
InChIKey
KYTREJMWHJPVSI-UHFFFAOYSA-N
CAS Number
CAS 116942-30-4
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Phosphodiesterase (PDE) 3 Target Info Modulator [533980]
References
Ref 526644Cardiovascular pharmacology of the vasodilator-cardiotonic agent, 349U85. J Cardiovasc Pharmacol. 1992 Oct;20(4):579-89.
Ref 533980Pharmacokinetics and pharmacodynamics of a new cardiotonic vasodilator agent, 349U85, in normal subjects. Clin Pharmacol Ther. 1994 Jan;55(1):55-63.
Ref 533980Pharmacokinetics and pharmacodynamics of a new cardiotonic vasodilator agent, 349U85, in normal subjects. Clin Pharmacol Ther. 1994 Jan;55(1):55-63.

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