| Drug General Information |
| Drug ID |
D0F5LH
|
| Former ID |
DNC001082
|
| Drug Name |
Oxybutynine
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C22H31NO3
|
| Canonical SMILES |
CCN(CC)CC#CCOC(=O)C(C1CCCCC1)(C2=CC=CC=C2)O
|
| InChI |
1S/C22H31NO3/c1-3-23(4-2)17-11-12-18-26-21(24)22(25,19-13-7-5-8-14-19)20-15-9-6-10-16-20/h5,7-8,13-14,20,25H,3-4,6,9-10,15-18H2,1-2H3
|
| InChIKey |
XIQVNETUBQGFHX-UHFFFAOYSA-N
|
| CAS Number |
CAS 152121-47-6
|
| PubChem Compound ID |
|
| PubChem Substance ID |
9564, 5214241, 7847531, 7980231, 8152846, 11466315, 11467435, 11486149, 14778874, 29223723, 46508005, 47285408, 47583256, 47656608, 47730755, 47953970, 48416365, 49698419, 49878667, 50105262, 50879481, 53788179, 56464138, 57322366, 85209626, 85788444, 90341037, 92721156, 99246155, 103376533, 104050614, 104253361, 104306976, 118048886, 124750101, 124757479, 124880981, 124880982, 124880984, 125164283, 125353222, 126619405, 126645204, 126669536, 127315550, 127315551, 127315552, 127315553, 127315554, 129694220
|
| SuperDrug ATC ID |
G04BD04
|
| SuperDrug CAS ID |
cas=005633205
|
| Target and Pathway |
| Target(s) |
Muscarinic acetylcholine receptor M3 |
Target Info |
Antagonist |
[1]
|
|---|
|
KEGG Pathway
|
Calcium signaling pathway
|
|
Neuroactive ligand-receptor interaction
|
|
Cholinergic synapse
|
|
Regulation of actin cytoskeleton
|
|
Insulin secretion
|
|
Salivary secretion
|
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Gastric acid secretion
|
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Pancreatic secretion
|
|
PANTHER Pathway
|
Alzheimer disease-amyloid secretase pathway
|
|
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
|
|
Muscarinic acetylcholine receptor 1 and 3 signaling pathway
|
|
PathWhiz Pathway
|
Gastric Acid Production
|
|
Reactome
|
Muscarinic acetylcholine receptors
|
|
Acetylcholine regulates insulin secretion
|
|
G alpha (q) signalling events
|
|
WikiPathways
|
Monoamine GPCRs
|
|
Calcium Regulation in the Cardiac Cell
|
|
Regulation of Actin Cytoskeleton
|
|
GPCRs, Class A Rhodopsin-like
|
|
Gastrin-CREB signalling pathway via PKC and MAPK
|
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Integration of energy metabolism
|
|
GPCR ligand binding
|
|
GPCR downstream signaling
|
|
GPCRs, Other
|
| References |
| REF 1 | Generation of an agonistic binding site for blockers of the M(3) muscarinic acetylcholine receptor. Biochem J. 2008 May 15;412(1):103-12. |
|---|
