Drug Information
Drug General Information | |||||
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Drug ID |
D0F1VQ
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Former ID |
DIB003966
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Drug Name |
ZIFROSILONE
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Synonyms |
MDL-73745; Zifrosilone < Rec INN; 2,2,2-Trifluoro-1-[3-(trimethylsilyl)phenyl]ethanone
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Drug Type |
Small molecular drug
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Indication | Cognitive disorders [ICD9: 290-294, 294.0, 780.09, 780.9, 780.93; ICD10:F01-F07, F04, F05, R41.3] | Discontinued in Phase 2 | [545006] | ||
Structure |
Download2D MOL |
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Formula |
C11H13F3OSi
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Canonical SMILES |
C[Si](C)(C)C1=CC=CC(=C1)C(=O)C(F)(F)F
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InChI |
1S/C11H13F3OSi/c1-16(2,3)9-6-4-5-8(7-9)10(15)11(12,13)14/h4-7H,1-3H3
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InChIKey |
GAPOASFZXBWUGS-UHFFFAOYSA-N
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CAS Number |
CAS 132236-18-1
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Acetylcholinesterase | Target Info | Inhibitor | [533665], [551871] | |
KEGG Pathway | Glycerophospholipid metabolism | ||||
Cholinergic synapse | |||||
Pathway Interaction Database | ATF-2 transcription factor network | ||||
PathWhiz Pathway | Phospholipid Biosynthesis | ||||
References |
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