TTD | Drug: D0EZ2W

Drug General Information
Drug ID	D0EZ2W
Former ID	DNC014552
Drug Name	CR-2345
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[551253]
Structure		Download 2D MOL 3D MOL
Formula	C26H37Cl3N4O3
Canonical SMILES	CN1CCN(CC1)C(=O)CCC(C(=O)N2CCC3(CCCC3)CC2)NC(=O)C4=CC(=<br />CC(=C4)Cl)Cl.Cl
InChI	1S/C26H36Cl2N4O3.ClH/c1-30-12-14-31(15-13-30)23(33)5-4-22(29-24(34)19-16-20(27)18-21(28)17-19)25(35)32-10-8-26(9-11-32)6-2-3-7-26;/h16-18,22H,2-15H2,1H3,(H,29,34);1H
InChIKey	FXORBQJCRPUVDJ-UHFFFAOYSA-N
PubChem Compound ID	45265542
Target and Pathway
Target(s)	Cholecystokinin receptor type A	Target Info	Inhibitor	[551253]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Insulin secretion
	Pancreatic secretion
Reactome	Peptide ligand-binding receptors
Reactome	G alpha (q) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 551253	Biological properties of (R)-4-benzamido-5-oxopentanoic basic derivatives as CCK-antagonists, Bioorg. Med. Chem. Lett. 3(5):861-866 (1993).
Ref 551253	Biological properties of (R)-4-benzamido-5-oxopentanoic basic derivatives as CCK-antagonists, Bioorg. Med. Chem. Lett. 3(5):861-866 (1993).

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Drug Information