Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0EG1F
|
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| Former ID |
DIB008799
|
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| Drug Name |
GR-199114X
|
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| Drug Type |
Small molecular drug
|
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| Indication | Stomach ulcer [ICD10:K25-K27] | Terminated | [1] | ||
| Company |
Glaxo Wellcome plc
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C28H32FN5O4
|
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| Canonical SMILES |
N1(C(=O)[C@@H](C(=O)N(c2c1cccc2)C1CCCCC1)NC(=O)Nc1ccc(F<br />)cc1)CC(=O)N1CCCC1
|
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| CAS Number |
CAS 162271-54-7
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Gastrin/cholecystokinin type B receptor | Target Info | Modulator | [2] | |
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Gastric acid secretion | |||||
| PANTHER Pathway | CCKR signaling map ST | ||||
| PathWhiz Pathway | Gastric Acid Production | ||||
| Reactome | Peptide ligand-binding receptors | ||||
| G alpha (q) signalling events | |||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| Secretion of Hydrochloric Acid in Parietal Cells | |||||
| Peptide GPCRs | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| GPCRs, Other | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009210) | ||||
| REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009210) | ||||
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