Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0EE8V
|
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| Former ID |
DNCL003484
|
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| Drug Name |
JNJ-42756493
|
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| Indication | Lymphoma [ICD9: 202.8, 208.9; ICD10:C81-C86] | Phase 1/2 | [1] | ||
| Company |
Janssen Research & Development
|
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| Structure |
|
Download2D MOL |
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| Target and Pathway | |||||
| Target(s) | Basic fibroblast growth factor receptor 1 | Target Info | Modulator | [2] | |
| KEGG Pathway | MAPK signaling pathway | ||||
| Ras signaling pathway | |||||
| Rap1 signaling pathway | |||||
| PI3K-Akt signaling pathway | |||||
| Adherens junction | |||||
| Signaling pathways regulating pluripotency of stem cells | |||||
| Regulation of actin cytoskeleton | |||||
| Pathways in cancer | |||||
| Proteoglycans in cancer | |||||
| Prostate cancer | |||||
| Melanoma | |||||
| Central carbon metabolism in cancer | |||||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| FGF signaling pathway | |||||
| Pathway Interaction Database | Glypican 1 network | ||||
| Syndecan-4-mediated signaling events | |||||
| N-cadherin signaling events | |||||
| FGF signaling pathway | |||||
| WikiPathways | Regulation of Actin Cytoskeleton | ||||
| Endochondral Ossification | |||||
| MAPK Signaling Pathway | |||||
| Mesodermal Commitment Pathway | |||||
| Hair Follicle Development: Induction (Part 1 of 3) | |||||
| Integrated Pancreatic Cancer Pathway | |||||
| Signaling Pathways in Glioblastoma | |||||
| Neural Crest Differentiation | |||||
| Signaling by FGFR | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800036975) | ||||
| REF 2 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1808). | ||||
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