Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0E8JM
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| Former ID |
DNC002689
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| Drug Name |
3-Sulfinoalanine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C3H7NO4S
|
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| InChI |
InChI=1S/C3H7NO4S/c4-2(3(5)6)1-9(7)8/h2H,1,4H2,(H,5,6)(H,7,8)
|
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| InChIKey |
ADVPTQAUNPRNPO-UHFFFAOYSA-N
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| CAS Number |
CAS 1115-65-7
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
4974500, 8150461, 16769113, 24278312, 24438489, 25631020, 46500456, 53789048, 57319964, 78144865, 85085077, 90456667, 103132083, 104293877, 117543597, 124801327, 125538854, 125948328, 127392137, 135058576, 135065510, 136352294, 137008071, 142679811, 144024037, 162022479, 162227733, 178101408, 178125665, 179294069, 179500963, 184576755, 215745189, 226765935, 242421046
|
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| Target and Pathway | |||||
| Target(s) | Hydroxymethylglutaryl-CoA synthase, mitochondrial | Target Info | Inhibitor | [2] | |
| Peptide deformylase | Target Info | Inhibitor | [2] | ||
| Glutathione reductase, mitochondrial | Target Info | Inhibitor | [2] | ||
| BioCyc Pathway | Superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) | ||||
| Superpathway of cholesterol biosynthesis | |||||
| Mevalonate pathway | |||||
| Ketogenesis | |||||
| KEGG Pathway | Synthesis and degradation of ketone bodies | ||||
| Valine, leucine and isoleucine degradation | |||||
| Butanoate metabolism | |||||
| Terpenoid backbone biosynthesis | |||||
| Metabolic pathways | |||||
| Biosynthesis of antibiotics | |||||
| PPAR signaling pathway | |||||
| Pathway Interaction Database | Validated targets of C-MYC transcriptional repression | ||||
| PathWhiz Pathway | Butyrate Metabolism | ||||
| Ketone Body Metabolism | |||||
| Valine, Leucine and Isoleucine Degradation | |||||
| Circadian clock | |||||
| Reactome | PPARA activates gene expression | ||||
| WikiPathways | Synthesis and Degradation of Ketone Bodies | ||||
| Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | |||||
| Fatty acid, triacylglycerol, and ketone body metabolism | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4695). | ||||
| REF 2 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | ||||
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