Drug General Information
Drug ID	D0E7BP
Former ID	DIB000118
Drug Name	CP-663427
Synonyms	LNK-427; OSI-427
Indication	Cancer [ICD9: 140-229; ICD10:C00-C96]		Terminated	[547153]
Company	Pfizer Inc
Structure		Download 2D MOL 3D MOL
Canonical SMILES	n1(c(=O)cc(c2c1ccc(C(c1n(cnc1)C)(c1cnc(cc1)Cl)N)c2)c1cc<br />(Cl)ccc1)CC1CC1
CAS Number	CAS 288391-21-9
Target and Pathway
Target(s)	Protein farnesyltransferase beta subunit	Target Info	Inhibitor	[550155]
KEGG Pathway	Terpenoid backbone biosynthesis
	Biosynthesis of antibiotics
NetPath Pathway	TSH Signaling Pathway
Reactome	Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways	Visual phototransduction
References
Ref 547153	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013446)
Ref 550155	WO patent application no. 2011,0881,26, Treatment of viral infection with prenyltransferase inhibitors.

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