Drug Information
Drug General Information | |||||
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Drug ID |
D0E6YQ
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Former ID |
DAP000558
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Drug Name |
Tacrine
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Synonyms |
Cognex; Romotal; Tacrina; Tacrinal; Tacrinum; Tenakrin; Tetrahydroaminacrine; Tetrahydroaminoacridine; Tetrahydroaminocrin; Tetrahydroaminocrine; Tha; Tacrine hydrochloride; BBL001044; CS 12602; Cognex (TN); Tacrina [INN-Spanish]; Tacrinal (TN); Tacrine (INN); Tacrine [INN:BAN]; Tacrinum [INN-Latin]; 1,2,3,4-TETRAHYDRO-9-ACRIDINAMINE; 1,2,3,4-TETRAHYDRO-9-ACRIDINAMINE (SEE ALSO 1684-40-8); 1,2,3,4-Tetrahydro-9-acridineamine; 1,2,3,4-Tetrahydro-acridin-9-ylamine; 1,2,3,4-Tetrahydroaminoacridine; 1,2,3,4-tetrahydroacridin-9-amine; 5-Amino-6,7,8,9-tetrahydroacridine (European); 9-AMINOTETRAHYDROACRIDINE; 9-Acridinamine, 1,2,3,4-tetrahydro-(9CI); 9-Amino-1,2,3,4-Tetrahydroacridine Hydrate Hydrochloride Hydrate; 9-amino-1,2,3,4-tetrahydroacridine
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Drug Type |
Small molecular drug
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Therapeutic Class |
Parasympathomimetics
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Structure |
Download2D MOL |
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Formula |
C13H14N2
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InChI |
InChI=1S/C13H14N2/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1,3,5,7H,2,4,6,8H2,(H2,14,15)
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InChIKey |
YLJREFDVOIBQDA-UHFFFAOYSA-N
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CAS Number |
CAS 321-64-2
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PubChem Compound ID | |||||
PubChem Substance ID |
4630, 597209, 3249865, 7423820, 7890757, 7980766, 8151345, 10518487, 10589113, 11110734, 11113824, 11336111, 11361350, 11363310, 11365872, 11368434, 11372617, 11374476, 11376596, 11451154, 11462322, 11466357, 11467477, 11485559, 11485994, 11489628, 11491524, 11492634, 11494230, 15120928, 24339135, 26697094, 26746578, 26751997, 26751998, 29221124, 46392558, 46393827, 46393828, 46505487, 46509736, 47291206, 47365271, 47440346, 47440347, 47515380, 47515381, 47589065, 47736566, 47736567
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ChEBI ID |
ChEBI:45980
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SuperDrug ATC ID |
N06DA01
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SuperDrug CAS ID |
cas=000321642
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Target and Pathway | |||||
Target(s) | Acetylcholinesterase | Target Info | Inhibitor | [535519] | |
KEGG Pathway | Glycerophospholipid metabolism | ||||
Cholinergic synapse | |||||
Pathway Interaction Database | ATF-2 transcription factor network | ||||
PathWhiz Pathway | Phospholipid Biosynthesis | ||||
References | |||||
Ref 536361 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. | ||||
Ref 541792 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6687). |
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