Drug General Information |
Drug ID |
D0E6XR
|
Former ID |
DAP000004
|
Drug Name |
Dasatinib
|
Synonyms |
Dasatinibum; Sprycel; Spyrcel; Dasatinib [USAN]; Dasatinib anhydrous; BMS 354825; BMS354825; BMS-354825; Dasatinib (USAN); Dasatinib, BMS 354825; SPRYCEL (TN); Sprycel (TN); BMS-354825, Sprycel, BMS354825, Dasatinib; N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide, monohydrate; N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide; N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide; N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide; N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE; (18F)-N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide; 2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide; Tyrosine Kinase Inhibitor - Ns
|
Drug Type |
Small molecular drug
|
Therapeutic Class |
Anticancer Agents
|
Company |
Bristol Myers Squibb
|
Structure |
|
Download
2D MOL
3D MOL
|
Formula |
C22H26ClN7O2S
|
InChI |
InChI=1S/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h3-5,12-13,31H,6-11H2,1-2H3,(H,28,32)(H,24,25,26,27)
|
InChIKey |
ZBNZXTGUTAYRHI-UHFFFAOYSA-N
|
CAS Number |
CAS 302962-49-8
|
PubChem Compound ID |
|
PubChem Substance ID |
10061134, 12015788, 14859389, 17397755, 17422520, 36127155, 46505143, 46513626, 47883136, 48429642, 49742622, 50070229, 50070567, 50071309, 50100097, 50125840, 52995488, 53799228, 56312240, 56312839, 56313127, 56373968, 56459420, 57288451, 57354110, 57551950, 74374210, 85246174, 87235888, 87357382, 93581026, 99381604, 99437986, 103501621, 103905543, 111644212, 117418208, 117695728, 118050493, 119503515, 124361516, 124756940, 124893650, 124893651, 124893652, 125001912, 125163747, 125264620, 125347447, 126624063
|
ChEBI ID |
ChEBI:49375
|
SuperDrug ATC ID |
L01XE06
|
Drug Resistance Mutation (DRM) |
Target and Pathway |
References |