Drug General Information
Drug ID	D0E5UQ
Former ID	DIB018264
Drug Name	[3H]CNQX
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[540676]
Structure		Download 2D MOL 3D MOL
Formula	C9H4N4O4
InChI	InChI=1S/C9H4N4O4/c10-3-4-1-5-6(2-7(4)13(16)17)12-9(15)8(14)11-5/h1-2H,(H,11,14)(H,12,15)
InChIKey	RPXVIAFEQBNEAX-UHFFFAOYSA-N
PubChem Compound ID	3721046
Target and Pathway
Target(s)	Glutamate receptor 1	Target Info	Antagonist	[543827]
	Glutamate receptor 3	Target Info	Modulator	[543829]
	Glutamate receptor 4	Target Info	Modulator	[543830]
	Glutamate receptor 2	Target Info	Antagonist	[543828]
KEGG Pathway	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Circadian entrainment
	Long-term potentiation
	Retrograde endocannabinoid signaling
	Glutamatergic synapse
	Dopaminergic synapse
	Long-term depression
	Amyotrophic lateral sclerosis (ALS)
	Amphetamine addiction
	Nicotine addictionhsa04024:cAMP signaling pathway
	Nicotine addiction
NetPath Pathway	IL2 Signaling Pathway
PANTHER Pathway	Ionotropic glutamate receptor pathway
	Metabotropic glutamate receptor group III pathwayP00037:Ionotropic glutamate receptor pathway
	Metabotropic glutamate receptor group III pathway
Pathway Interaction Database	EPHB forward signalingncadherinpathway:N-cadherin signaling events
Reactome	COPII (Coat Protein 2) Mediated Vesicle Transport
	Trafficking of AMPA receptors
	Trafficking of GluR2-containing AMPA receptors
	Unblocking of NMDA receptor, glutamate binding and activation
	Cargo concentration in the ERR-HSA-399719:Trafficking of AMPA receptors
WikiPathways	Hypothetical Network for Drug Addiction
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Amyotrophic lateral sclerosis (ALS)
	BDNF signaling pathwayWP666:Hypothetical Network for Drug Addiction
References
Ref 540676	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4081).
Ref 543827	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 444).
Ref 543828	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 445).
Ref 543829	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 446).
Ref 543830	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 447).

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