Drug General Information
Drug ID
D0E2OK
Former ID
DIB016921
Drug Name
MAL formulation
Synonyms
MAL formulation (oral, opiate dependence)
Indication Opiate dependence [ICD9: 304; ICD10:F11] Phase 2 [550591]
Company
D&A Pharma
Target and Pathway
Target(s) Mu-type opioid receptor Target Info Agonist [550590]
Kappa-type opioid receptor Target Info Agonist [550590]
KEGG Pathway Neuroactive ligand-receptor interaction
Estrogen signaling pathway
Morphine addictionhsa04080:Neuroactive ligand-receptor interaction
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Enkephalin releaseP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Opioid prodynorphin pathway
Pathway Interaction Database IL4-mediated signaling events
Reactome Peptide ligand-binding receptors
G alpha (i) signalling eventsR-HSA-375276:Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways TCR Signaling Pathway
GPCRs, Class A Rhodopsin-like
Peptide GPCRs
Opioid Signalling
GPCR ligand binding
GPCR downstream signalingWP455:GPCRs, Class A Rhodopsin-like
GPCR downstream signaling
References
Ref 550591Clinical pipeline report, company report or official report of D&A Pharma.
Ref 550590Clinical pipeline report, company report or official report of D&A Pharma.

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