Drug Information

Drug General Information
Drug ID
D0D9JW
Former ID
DAP000618
Drug Name
Ketorolac
Synonyms
Ketoralac; Ketorolaco; Ketorolacum; Macril; Ketorolaco [Spanish]; Ketorolacum [Latin]; RS 37619; Acular (TN); Ketorolac (INN); Ketorolac [INN:BAN]; RS-37619; Toradol (TN); (+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid; (+-)-Ketorolac; (+-)-isomer; (+/-)-2,3-Dihydro-5-benzoyl-1H-pyrrolizine-1-carboxylic acid; 1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro; 5-(phenylcarbonyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid; 5-Benzoyl-1,2-dihydro-3H-pyrrolo(1,2a)pyrrole-1-carboxylic acid; 5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
Drug Type
Small molecular drug
Indication Postoperative inflammation undergone cataract extraction Approved [551871]
Therapeutic Class
Analgesics
Company
Laboratorios Syntex SA
Structure
Download
2D MOL

3D MOL
Formula
C15H13NO3
InChI
InChI=1S/C15H13NO3/c17-14(10-4-2-1-3-5-10)13-7-6-12-11(15(18)19)8-9-16(12)13/h1-7,11H,8-9H2,(H,18,19)
InChIKey
OZWKMVRBQXNZKK-UHFFFAOYSA-N
CAS Number
CAS 66635-83-4
PubChem Compound ID
3826
PubChem Substance ID
9274, 5316934, 7979681, 8152424, 12013083, 14774471, 29222945, 46507019, 48416148, 49698948, 50040043, 50559242, 53787558, 56313647, 57322012, 85787389, 87245106, 90341692, 92719330, 96024794, 99281833, 103168363, 103922837, 104304637, 118314823, 124749910, 124896716, 125357028, 126449597, 126449602, 126621065, 126628266, 126648434, 126657726, 126670368, 126670856, 128885449, 131939830, 134337908, 135011243, 135039632, 136351611, 137035346, 142342166, 160654547, 160963811, 162178870, 162631206, 163414850, 164827307
SuperDrug ATC ID
M01AB15; S01BC05
SuperDrug CAS ID
cas=074103063
Target and Pathway
Target(s) Cyclooxygenase Target Info Inhibitor [536379]
References
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 536379Cyclooxygenase and nitric oxide synthase dependence of cutaneous reactive hyperemia in humans. Am J Physiol Heart Circ Physiol. 2007 Jul;293(1):H425-32. Epub 2007 Mar 16.

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