Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0D6GI
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| Former ID |
DNC010849
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| Drug Name |
1-(3-CHLORO-4-FLUOROPHENYL)-2,2,2-TRIFLUORO-1-(1-(4-FLUOROPHENYL)-1H-INDAZOL-5-YL)ETHANOL (ENANTIOMERIC MIX)
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
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Download2D MOL |
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| Formula |
C21H12ClF5N2O
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | mRNA of glucocorticoid receptor | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| TCR Signaling Pathway | |||||
| Pathway Interaction Database | Regulation of nuclear SMAD2/3 signaling | ||||
| Signaling events mediated by HDAC Class II | |||||
| FOXA2 and FOXA3 transcription factor networks | |||||
| Glucocorticoid receptor regulatory network | |||||
| Regulation of Androgen receptor activity | |||||
| AP-1 transcription factor network | |||||
| Reactome | BMAL1:CLOCK,NPAS2 activates circadian gene expression | ||||
| WikiPathways | Serotonin Receptor 4/6/7 and NR3C Signaling | ||||
| SIDS Susceptibility Pathways | |||||
| Endoderm Differentiation | |||||
| Hair Follicle Development: Cytodifferentiation (Part 3 of 3) | |||||
| Adipogenesis | |||||
| Circadian Clock | |||||
| Nuclear Receptors | |||||
| References | |||||
| REF 1 | Bioorg Med Chem Lett. 2010 May 15;20(10):3017-20. Epub 2010 Apr 11.5-Functionalized indazoles as glucocorticoid receptor agonists. | ||||
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