Drug Information

Drug General Information
Drug ID
D0D5QP
Former ID
DIB020157
Drug Name
L-366,509
Synonyms
L-366509
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539419]
Structure
Download
2D MOL
Formula
C25H33NO5S
InChI
InChI=1S/C25H33NO5S/c1-22(2)19-8-10-24(22,25(29,15-19)16-21(27)28)17-32(30,31)26-13-11-23(12-14-26)9-7-18-5-3-4-6-20(18)23/h3-7,9,19,29H,8,10-17H2,1-2H3,(H,27,28)
InChIKey
XKVDTEPESVJNPJ-UHFFFAOYSA-N
PubChem Compound ID
3083288
PubChem Substance ID
36413727, 74734926, 85214911, 111687305, 135229792, 135650468, 224941910, 230835349
Target and Pathway
Target(s) Oxytocin receptor Target Info Antagonist [533590]
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Oxytocin signaling pathway
NetPath Pathway TGF_beta_Receptor Signaling Pathway
PANTHER Pathway Oxytocin receptor mediated signaling pathway
Reactome Vasopressin-like receptors
G alpha (q) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Myometrial Relaxation and Contraction Pathways
Oxytocin signaling
Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 539419(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2242).
Ref 533590Characterization of the human oxytocin receptor stably expressed in 293 human embryonic kidney cells. Life Sci. 1995;57(24):2253-61.

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