TTD | Drug: D0CS4I

Drug General Information
Drug ID	D0CS4I
Former ID	DIB018481
Drug Name	15(R)-15-methyl-PGD2
Synonyms	15R-15-methyl PGD2
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539203]
Structure		Download 2D MOL
Formula	C21H34O5
InChI	InChI=1S/C21H34O5/c1-3-4-9-13-21(2,26)14-12-17-16(18(22)15-19(17)23)10-7-5-6-8-11-20(24)25/h5,7,12,14,16-18,22,26H,3-4,6,8-11,13,15H2,1-2H3,(H,24,25)/b7-5-,14-12+/t16-,17-,18+,21-/m1/s1
InChIKey	CTXLUMAOXBULOZ-BKVRKCTKSA-N
PubChem Compound ID	5283097
PubChem Substance ID	4266033, 11038743, 16501532, 39316513, 76979650, 113859082, 135649652, 179656259, 241052161, 252457433, 252464091
Target and Pathway
Target(s)	Putative G-protein coupled receptor 44	Target Info	Agonist	[527831]
Reactome	Prostanoid ligand receptors
Reactome	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 539203	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1902).
Ref 527831	CRTH2-specific binding characteristics of [3H]ramatroban and its effects on PGD2-, 15-deoxy-Delta12, 14-PGJ2- and indomethacin-induced agonist responses. Eur J Pharmacol. 2005 Nov 7;524(1-3):30-7. Epub 2005 Oct 27.

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Drug Information