Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0CR9I
|
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| Former ID |
DIB011106
|
||||
| Drug Name |
CX-5011
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Cancer [ICD9: 140-229; ICD10:C00-C96] | Investigative | [1] | ||
| Company |
Cylene Pharmaceuticals Inc
|
||||
| Structure |
|
Download2D MOL |
|||
| Formula |
C20H11N4NaO2
|
||||
| Canonical SMILES |
c1ncc2c(n1)c(nc1c2ccc(c1)C(=O)O)Nc1cc(ccc1)C#C
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Casein kinase II, alpha chain | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Ribosome biogenesis in eukaryotes | ||||
| NF-kappa B signaling pathway | |||||
| Wnt signaling pathway | |||||
| Adherens junction | |||||
| Tight junction | |||||
| Measles | |||||
| Herpes simplex infection | |||||
| Epstein-Barr virus infection | |||||
| NetPath Pathway | FSH Signaling Pathway | ||||
| Pathway Interaction Database | BCR signaling pathway | ||||
| Atypical NF-kappaB pathway | |||||
| DNA-PK pathway in nonhomologous end joining | |||||
| Presenilin action in Notch and Wnt signaling | |||||
| Role of Calcineurin-dependent NFAT signaling in lymphocytes | |||||
| E-cadherin signaling in the nascent adherens junction | |||||
| Lissencephaly gene (LIS1) in neuronal migration and development | |||||
| PDGFR-alpha signaling pathway | |||||
| Signaling mediated by p38-alpha and p38-beta | |||||
| Alpha-synuclein signaling | |||||
| Reactome | Condensation of Prometaphase Chromosomes | ||||
| WikiPathways | Mitotic Prometaphase | ||||
| BDNF signaling pathway | |||||
| TNF alpha Signaling Pathway | |||||
| L1CAM interactions | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1549). | ||||
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