Drug General Information
Drug ID	D0CR9I
Former ID	DIB011106
Drug Name	CX-5011
Drug Type	Small molecular drug
Indication	Cancer [ICD9: 140-229; ICD10:C00-C96]		Investigative	[543439]
Company	Cylene Pharmaceuticals Inc
Structure		Download 2D MOL 3D MOL
Formula	C20H11N4NaO2
Canonical SMILES	c1ncc2c(n1)c(nc1c2ccc(c1)C(=O)O)Nc1cc(ccc1)C#C
PubChem Compound ID	70702100
Target and Pathway
Target(s)	Casein kinase II, alpha chain	Target Info	Inhibitor	[543439]
KEGG Pathway	Ribosome biogenesis in eukaryotes
	NF-kappa B signaling pathway
	Wnt signaling pathway
	Adherens junction
	Tight junction
	Measles
	Herpes simplex infection
	Epstein-Barr virus infection
NetPath Pathway	FSH Signaling Pathway
Pathway Interaction Database	BCR signaling pathway
	Atypical NF-kappaB pathway
	DNA-PK pathway in nonhomologous end joining
	Presenilin action in Notch and Wnt signaling
	Role of Calcineurin-dependent NFAT signaling in lymphocytes
	E-cadherin signaling in the nascent adherens junction
	Lissencephaly gene (LIS1) in neuronal migration and development
	PDGFR-alpha signaling pathway
	Signaling mediated by p38-alpha and p38-beta
	Alpha-synuclein signaling
Reactome	Condensation of Prometaphase Chromosomes
WikiPathways	Mitotic Prometaphase
	BDNF signaling pathway
	TNF alpha Signaling Pathway
	L1CAM interactions
References
Ref 543439	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1549).
Ref 543439	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1549).

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