Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0C9DP
|
||||
| Former ID |
DNC006951
|
||||
| Drug Name |
ADS-103168
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C20H19F3N4O2
|
||||
| Canonical SMILES |
C1CCN(C1)C2=NC3=C(N2)C=C(C=C3)NC(=O)COC4=CC=C(C=C4)C(F)<br />(F)F
|
||||
| InChI |
1S/C20H19F3N4O2/c21-20(22,23)13-3-6-15(7-4-13)29-12-18(28)24-14-5-8-16-17(11-14)26-19(25-16)27-9-1-2-10-27/h3-8,11H,1-2,9-10,12H2,(H,24,28)(H,25,26)
|
||||
| InChIKey |
UWZAIHJEZDRIJB-UHFFFAOYSA-N
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Melanin-concentrating hormone receptor 1 | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Reactome | Peptide ligand-binding receptors | ||||
| G alpha (q) signalling events | |||||
| G alpha (i) signalling events | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | Bioorg Med Chem Lett. 2007 Mar 1;17(5):1403-7. Epub 2006 Dec 2.Quinazoline and benzimidazole MCH-1R antagonists. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.