Drug Information
Drug General Information | |||||
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Drug ID |
D0C7KK
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Former ID |
DCL000283
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Drug Name |
Zenarestat
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Synonyms |
ZES; Zenarestatum; FK 366; FR 74366; FR74366; Fk366; FK-366; FR-74366; Zenarestat [USAN:INN]; Zenarestatum [INN-Latin]; Zenarestat (USAN/INN); [3-(4-bromo-2-fluorobenzyl)-7-chloro-2,4-dioxo-3,4-dihydroquinazolin-1(2h)-yl]acetic acid; [3-(4-BROMO-2-FLUORO-BENZYL)-7-CHLORO-2,4-DIOXO-3,4-DIHYDRO-2H-QUINAZOLIN-1-YL]-ACETIC ACID; (3-(4-bromo-2-fluorobenzyl)-7-chloro-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-1-yl)acetic acid; 2-(7-Chloro-3-(4-bromo-2-fluorobenzyl)-1,2,3,4-tetrahydro-2,4-dioxoquinazolin)-1-acetic acid; 2-[3-[(4-bromo-2-fluorophenyl)methyl]-7-chloro-2,4-dioxoquinazolin-1-yl]acetic acid; 3-((4-Bromo-2-fluorophenyl)methyl)-7-chloro-3,4-dihydro-2,4-dioxo-1(2H)-quinazolineaceticacid; 3-(4-Bromo-2-fluorobenzyl)-7-chloro-3,4-dihydro-2,4-dioxo-1(2H)-quinazolineacetic acid
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Drug Type |
Small molecular drug
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Company |
Ono Pharmaceutical; Fujisawa Pharmaceutical
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Structure |
Download2D MOL |
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Formula |
C17H11BrClFN2O4
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InChI |
InChI=1S/C17H11BrClFN2O4/c18-10-2-1-9(13(20)5-10)7-22-16(25)12-4-3-11(19)6-14(12)21(17(22)26)8-15(23)24/h1-6H,7-8H2,(H,23,24)
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InChIKey |
SXONDGSPUVNZLO-UHFFFAOYSA-N
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CAS Number |
CAS 112733-06-9
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PubChem Compound ID | |||||
PubChem Substance ID |
822640, 5366122, 7891218, 8153507, 12014058, 14759400, 17397895, 29224761, 46507491, 46516730, 50040925, 50184937, 57322915, 103064709, 103085748, 103170569, 104310073, 117389120, 124954386, 126591590, 129303239, 134338939, 134340696, 135024687, 137183403, 142347545, 144210777, 160965347, 162311567, 163306697, 170466650, 178103990, 179149602, 184526342, 198947648, 224890862, 226432807
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Target and Pathway | |||||
Target(s) | Aldose reductase | Target Info | Inhibitor | [535187] | |
NetPath Pathway | IL1 Signaling Pathway | ||||
TGF_beta_Receptor Signaling Pathway | |||||
References | |||||
Ref 542442 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7418). | ||||
Ref 544507 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000004) |
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