Drug Information
Drug General Information | |||||
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Drug ID |
D0C6NM
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Former ID |
DAP001216
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Drug Name |
Latanoprost
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Synonyms |
Catioprost; Xalatan; Latanoprost free acid; L1167_SIGMA; PhXA41; XA41; AR-202; Nova-21027; PHXA-41; XA-41; Xalatan (TN); Latanoprost (JAN/USAN/INN); PhXA34 [as 15(R,S)-isomer]; Isopropyl (5Z,9alpha,11alpha,15R)-9,11,15-trihydroxy-17-phenyl-18,19,20-trinorprost-5-en-1-oate; Isopropyl (5Z,9alpha,11alpha,15R)-9,11,15-trihydroxy-17-phenyl-18,19,20-trinor-prost-5-en-1-oate; Isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3R)-3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoate; Propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate; Propan-2-yl (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}hept-5-enoate
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Drug Type |
Small molecular drug
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Therapeutic Class |
Antihypertensive Agents
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Company |
Pfizer Pharmaceuticals
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Structure |
Download2D MOL |
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Formula |
C23H34O5
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InChI |
InChI=1S/C23H34O5/c24-18(13-12-17-8-4-3-5-9-17)14-15-20-19(21(25)16-22(20)26)10-6-1-2-7-11-23(27)28/h1,3-6,8-9,18-22,24-26H,2,7,10-16H2,(H,27,28)/b6-1-/t18-,19+,20+,21-,22+/m0/s1
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InChIKey |
HNPFPERDNWXAGS-NFVOFSAMSA-N
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CAS Number |
CAS 130209-82-4
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
ChEBI ID |
ChEBI:6384
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SuperDrug ATC ID |
S01EE01
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SuperDrug CAS ID |
cas=130209824
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Target and Pathway | |||||
Target(s) | Prostaglandin F2-alpha receptor | Target Info | Agonist | [537255] | |
References | |||||
Ref 536361 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. | ||||
Ref 539258 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1961). | ||||
Ref 551115 | Clinical pipeline report, company report or official report of Mati therapeutics. | ||||
Ref 551493 | Clinical pipeline report, company report or official report of Pfizer. |
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