Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0C4VG
|
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| Former ID |
DNC014410
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| Drug Name |
4-phospho-D-erythronate
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C4H9O8P
|
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| Canonical SMILES |
C(C(C(C(=O)O)O)O)OP(=O)(O)O
|
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| InChI |
1S/C4H9O8P/c5-2(3(6)4(7)8)1-12-13(9,10)11/h2-3,5-6H,1H2,(H,7,8)(H2,9,10,11)/t2-,3-/m1/s1
|
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| InChIKey |
ZCZXOHUILRHRQJ-PWNYCUMCSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | 6-phosphogluconate dehydrogenase, decarboxylating | Target Info | Inhibitor | [1] | |
| BioCyc Pathway | Pentose phosphate pathway | ||||
| Pentose phosphate pathway (oxidative branch) | |||||
| KEGG Pathway | Pentose phosphate pathway | ||||
| Glutathione metabolism | |||||
| Metabolic pathways | |||||
| Biosynthesis of antibiotics | |||||
| Carbon metabolism | |||||
| PANTHER Pathway | Pentose phosphate pathway | ||||
| PathWhiz Pathway | Warburg Effect | ||||
| WikiPathways | NRF2 pathway | ||||
| Nuclear Receptors Meta-Pathway | |||||
| Metabolism of carbohydrates | |||||
| Pentose Phosphate Pathway | |||||
| References | |||||
| REF 1 | Virtual fragment screening for novel inhibitors of 6-phosphogluconate dehydrogenase. Bioorg Med Chem. 2010 Jul 15;18(14):5056-62. doi: 10.1016/j.bmc.2010.05.077. Epub 2010 Jun 9. | ||||
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